Cell Lines and Cell Cultures
ATCC Serratia liquefaciens
Type strain. Produces follicle-stimulating hormone binding inhibitor (FSH-BI). Quality control strain.
ATCC Providencia alcalifaciens
This culture is a bacterial type strain that was isolated from feces. It can be used in quality control testing and produces restriction endonuclease PalI.
ATCC Staphylococcus aureus; 6 x 0.3mL
ATCC BAA-976-MINI-PACK™ consists of 6 ready-to-use vials of ATCC BAA-976™ frozen in 200 μL of glycerol stock, eliminating the need to rehydrate and culture the strain prior to use. Each vial is provided with a 2-D barcode for easy storage and tracking, as well as peel-off labels for fast and reliable recordkeeping.
Eurofins Discoverx ChemiScreen CB2 Cannabinoid Receptor Membrane Preparation, 1 vial. (HTS020M)
The ChemiScreen CB2 Cannabinoid Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of CNR2 surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach or to screen for GPCR activity using GTPγS assays. Increased binding affinities or GPCR activation levels will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
Eurofins Discoverx PrecisION hHCN2 Recombinant Stable Cell Line, 2 vials. (CYL3041)
The PrecisION hHCN2 Recombinant Stable Cell Line is a stable, engineered cell line for use in studying HCN2 ion channels, including drug candidates which affect channel function. This cell line enables assessment of ion channel function via detection of electrophysiological signals. The included cell line overexpresses HCN2 ion channels. Upon ligand/agonist induced channel activation, response can be detected via automated or manual electrophysiological techniques. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/ion-channels.
Eurofins Discoverx ChemiScreen CX3CR1 Chemokine Receptor Membrane Preparation, 1 vial. (HTS015M)
The ChemiScreen CX3CR1 Chemokine Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of CX3CR1 surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
Eurofins Discoverx ChemiScreen TP Prostanoid Receptor Stable Cell Line, 2 vials. (HTS081C)
The ChemiScreen TP Prostanoid Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. prostaglandin H2, thromboxane A2) based activation of TBXA2R GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses TBXA2R alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of TBXA2R, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx ChemiScreen D2 Dopamine Receptor Membrane Preparation, 1 vial. (HTS039M)
The ChemiScreen D2 Dopamine Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of DRD2 surface expression. ChemiScreen membrane preps can be used to screen for GPCR activity using GTPγS assays. Increased GPCR activation levels will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.